在Python中搜索并替换文件中的一行

应该这样做。它基本上将内容写入新文件并用新文件替换旧文件：

from tempfile import mkstemp

from shutil import move

from os import fdopen, remove

def replace(file_path, pattern, subst):

#Create temp file

fh, abs_path = mkstemp()

with fdopen(fh,'w') as new_file:

    with open(file_path) as old_file:

        for line in old_file:

            new_file.write(line.replace(pattern, 

subst))

#Remove original file

remove(file_path)

#Move new file

move(abs_path, file_path)